Follow These Tips If You Are You Trying To Lose Weight : Premier ...

Posted by haleyjonas on Wednesday, September 19, 2012 ? Leave a Comment?

Weight loss is easily one of the most popular fitness topics, with numerous people committing to losing weight every day. The bottom line is, it is not a simple task to lose weight. This article can help you a lot in overcoming this and coming out lighter.

Pizza lovers should take note that there are alternatives to the calories carried by most pizzas. You canask for less cheese or make your own pizza at home with fat free cheese.

Exercise always needs to be a part in any weight loss plan. Exercise requires fuel, which means it burns calories. This will speed up your weight loss efforts and allow you to eat more, while still continuing to lose. Jogging and biking are fun ways to exercise and both activities burn a lot of calories. Resistance training will help tone your overall physique.

TIP! Whenever possible, opt to take the stairs to your destination. This can help you burn calories and stretches your muscles.

You can improve your odds of losing weight significantly by planning ahead. As with anything, there are going to be times when you are tempted. When you make your plan, come up with healthy, low calorie snacks to eat instead of the foods you are tempted to have.

Doing a physical activity along with your meals can help you lose more weight than diet alone. Interested in an afternoon picnic? Walk to a park to have it, providing yourself with a little exercise. Provided your schedule permits, coordinate your meals with vigorous activity so that you can work the calories off and keep your weight down.

If you are beginning a weight loss plan, as for help from someone to find out the diet that can work in your favor. Our bodies are all different, so you may not get the same results from one diet that someone else did. Seek outside help when trying to lose weight.

TIP! Take measures to enhance your weight loss plan while at work. If you have a sedentary job, you may get into the habit of sitting most of the time.

All diets do not work for everyone. Some people see quick and dramatic results from a low carb diet, while others see little if any change. However, you?re diet still needs to meet your needs and work for you.

Self-hypnosis can actually have a positive effect on your weight-loss program. It may sound far-fetched, but hypnosis can turn your life around and will make it much easier for you to make lifestyle changes.

Finding healthy food choices while traveling can be difficult. Bring your own healthy food instead of eating at roadside restaurants. Pack a cooler and include yogurt, fruit, veggies and granola bars. Foods like these keep well, pack easily and are not hard to eat when driving. Hydration during the trip is also important, so remember to pack some water.

TIP! When you feel the pangs of hunger, give yourself few minutes before you eat anything. Your body can feel hungry when it is simply bored or thirsty.

Make sure that you only eat when you are hungry and avoid comfort foods. Discover what emotions or circumstances are making you want to consume comfort food. Try to find something else you can do to help you feel better during these bad situations, such as exercising.

Turn your time on the phone into a weight loss workout. When you are talking on the phone, move around to burn calories. Calisthenics are not required. Just walk around the room or do a few chores, and the extra calories you burn will begin to add up over time.

Never drink soda pop. Loaded with carbohydrates and sugar, sodas can intensify your cravings. If you would like to shed those pounds, drink water to quench your thirst instead.

TIP! Losing weight does not have to be an impossible feat. Start by eliminating particular bad foods from your diet.

Eating a chunky soup instead of a meal can help you lose weight. Try to drink and eat your calories to moderate your consumption. By choosing chunky soups full of vegetables, beans, etc., you?ll notice that you?ll get fuller quicker instead of selecting creamy soups.

Wear comfortable shoes while exercising. You don?t want to hurt yourself or make yourself unnecessarily sore by wearing uncomfortable shoes that don?t fit right. These shoes do not have to be expensive. What you are looking for is a pair that fits well, feels good and provides adequate support.

Do not eat food too quickly if you desire to lose weight. To help you do this you should chew your food longer or take smaller pieces in your mouth, or just have a nice chat with someone while eating. You will notice a sense of fullness faster and you will eat just enough to be satiated, not stuffed.

TIP! Treating yourself for achieving milestones is critical for diet success. Take a night to yourself or go out with friends to get your mind off your diet regimen.

When you have cereal for breakfast at least five days of the week, you are likely to lose weight. These cereals contain fiber, along with vitamins and minerals, that are an essential part of a healthy diet. Look for the ones that offer the most benefit and stay clear of cereal that is high in sugar content. Stick with healthy, low-sugar cerals.

If you are trying to lose weight or get in better shape, this article can help you out. Remember, without continued exercise and portion control your weight can come back quickly.

If you are trying to shed some weight, it may be a good idea to put a little extra effort into exercises that work your cardiovascular system as opposed to weight training. While muscle building is great for helping you lose weight, cardio training is essential since it helps you burn large amounts of calories relatively easily. When losing weight, raising the rate of your heart and respiration are much more helpful as opposed to building muscle mass.

TIP! You should always have time in the morning to eat breakfast. If you are on the go, you may be tempted to reach for a pastry.

Source: http://pdfbox.org/follow-these-tips-if-you-are-you-trying-to-lose-weight/

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Lawyers in Pakistan rally against anti-Islam film

Afghan university students burn a U.S. flag in Surkhrod district of Nangarhar province, east of Kabul, Afghanistan, Wednesday, Sept 19, 2012. Hundreds of Afghans, some shouting "Death to America", held a protest against an anti-Islam film in the eastern city of Jalalabad. (AP Photo/Rahmat Gul)

Afghan university students burn a U.S. flag in Surkhrod district of Nangarhar province, east of Kabul, Afghanistan, Wednesday, Sept 19, 2012. Hundreds of Afghans, some shouting "Death to America", held a protest against an anti-Islam film in the eastern city of Jalalabad. (AP Photo/Rahmat Gul)

Afghan university students step over a U.S. flag in Surkhrod district of Nangarhar province, east of Kabul, Afghanistan, Wednesday, Sept. 19, 2012. Hundreds of Afghans, some shouting "Death to America", held a protest against an anti-Islam film in the eastern city of Jalalabad. (AP Photo/Rahmat Gul)

Muslim protesters throw eggs at a mock U.S. flag during a protest against American-made film "Innocence of Muslims" that ridicules Islam and Prophet Muhammad outside the U.S. Embassy in Jakarta, Indonesia, Wednesday, Sept. 19, 2012. (AP Photo/Tatan Syuflana)

Police officers watch as Muslim protesters hangs banners and a U.S. flag on the razor wire surrounding the U.S. Embassy compound during a protest against American-made film "Innocence of Muslims" that ridicules Islam and Prophet Muhammad in Jakarta, Indonesia, Wednesday, Sept. 19, 2012. (AP Photo/Tatan Syuflana)

Kashmiri medical students protest against an anti-Islam film called "Innocence of Muslims" that ridicules Islam's Prophet Muhammad Wednesday, Sept. 19, 2012, in Srinagar, India. (AP Photo/Mukhtar Khan)

ISLAMABAD (AP) ? Several hundred lawyers protesting an anti-Islam video forced their way into an area in Pakistan's capital that houses the U.S. Embassy and other foreign missions on Wednesday, and the United States temporarily closed its consulate in an Indonesian city because of similar demonstrations.

The lawyers who protested in Islamabad shouted anti-U.S. slogans and burned an American flag after they pushed through a gate, gaining access to the diplomatic enclave before police stopped them. They called for the U.S. ambassador to be expelled from the country, and then peacefully dispersed.

The demonstration followed three days of violent protests against the film in Pakistan in which two people were killed. At least 28 other people have died in violence linked to the film in seven countries, including U.S. Ambassador Christopher Stevens and three other Americans killed in a Sept. 11 attack on the U.S. Consulate in Benghazi, Libya.

Much of the anger over the film, which denigrates Islam's Prophet Muhammad, has been directed at the U.S. government even though the film was privately produced in the United States and American officials have criticized it.

The U.S. Embassy in Indonesia sent a text message to U.S. citizens saying that the consulate in Medan, the country's third-largest city, has been closed temporarily because of demonstrations over the film, "Innocence of Muslims."

About 300 members of Hizbut Tahrir Indonesia, a pan-Islamic movement, rallied peacefully on Wednesday in front of the consulate in Medan, the capital of North Sumatra province. Later, about 50 Muslim students also protested there. Both groups called on Washington to punish the makers of the film.

It was the third consecutive day of protests in Medan. On Monday, protesters hurled rocks and Molotov cocktails outside the embassy in Jakarta, the capital.

In France, the government has barred a planned protest by people angry over the anti-Islam film, but defended a newspaper's right to publish caricatures of the prophet.

France's foreign minister said security is being stepped up at some French embassies amid tensions in France and elsewhere around the film. French authorities and Muslim leaders urged calm in the country, which has the largest Muslim population in western Europe.

Riot police took up positions outside the Paris offices of a satirical French weekly that published crude caricatures of the Prophet Muhammad on Wednesday that ridicule the film and the furor surrounding it. The provocative weekly, Charlie Hebdo, was firebombed last year after it released a special edition that portrayed the Prophet Muhammad as a "guest editor" and took aim at radical Islam.

The investigation into that attack is still under way.

Prime Minister Jean-Marc Ayrault of France said organizers of a planned demonstration Saturday against the film won't receive police authorization. Ayrault told French radio RTL that "there's no reason for us to let a conflict that doesn't concern France come into our country. We are a republic that has no intention of being intimidated by anyone."

On Tuesday, Islamic militants sought to capitalize on anger over the film, saying a suicide bombing that killed 12 people in Afghanistan was revenge for the video and calling for attacks on U.S. diplomats and facilities in North Africa.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-09-19-Prophet%20Film/id-1f7be1ecec0c4f8db3c5fc08b9643e81

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Cheap Car Insurance ~ Travel Bug's Sense

With gas prices being the way they have people all over the country have started to get creative with their finances and the costs associated with auto travel.

Prices vary from company to company, so it pays to shop around. Get at least four to five price quotes. You will find that there are several websites out there that can save you the time from doing this the slow and hard way as they will often get you quotes from up to a dozen companies all at once. You can call companies directly or access information on the Internet. Your state insurance department may also provide comparisons of prices charged by major insurers. And no, companies like Progressive that claim they will compare other companies, but they are an insurance company, so they are not to be trusted. They only have one interest, and that is to promote their own business.

One of the best ways to get cheap car insurance is simply to use a service that forces insurance agents and brokers to compete against one another. At the end of this article is one example of such a site. As soon as you finish your online quote request, multiple agents will contact you. But it is important to NOT sign up with any one of them immediately-Instead, let them know that you are awaiting calls from other local insurance providers. After 5 or so of these people have contacted you, you should have a good idea of what sort of range you might expect to pay.


Then, if you really want to get the cheapest car insurance possible, simply tell the agents that you are ready to buy within the next 24 hours with whichever company offers you the lowest insurance rates. This really puts the fire under them, and is sure to create the most optimal pricing for you. Of course, be sure to carry through on your promise.

If it makes sense, you may want to consider getting a bundle package. Basically, see what it might cost to insure not only your car, but also your home, property, health and life insurance. This can save a person around 10% - 30% depending on the company you go with; and it does make paying your bills easier as well.

Oh, and one more tip, remember that the more info you provide upfront, the more accurate your quotes will be, and the more likely the insurance companies will be responsive to your inquiry. This is especially true when filling out a quote from multiple companies.

Source: http://saturdayspotlight.blogspot.com/2012/09/cheap-car-insurance.html

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Getting Far better At Email Marketing With One Of ... - Business Articles

This article has been viewed 9 times.

Becoming Far better At Email Marketing By Using These Fantastic Ideas

Since most people is on the computer systems consistently and also checking their e-mails, email marketing is a very smart choice to your firm. Put into action these guidelines should you be interested in beginning an email marketing marketing campaign.

Covering up all bases when it comes to e-mail marketing needs making use of multiple-part messages. These are emails that come with equally Web coding and simple written text articles, so that they will display appropriately regardless of what choice the receiver of the email mementos. This really is straightforward to do, and it will help to keep every one of the subscribers on your own checklist delighted.

From time to time, make positive changes to structure in order to provide even more of a personal effect. If you use Web coding with your information, attempt sending out an elementary textual content e-mail as an alternative. If you use nicely-composed textual content, this sort of information can have a romantic really feel, that can often make the consumers see you in an a lot more private and relying way.

Spot a prominent unsubscribe hyperlink within your e-mail information so buyers can easily get off your collection, if they don?t want your information any longer. Even though the price is small, email marketing mailings do charge funds. You?ll also harm your status, resulting in your profits to lessen and prospective backlash including appearing with an electronic mail blacklist.

In order to guarantee that each individual buyer on your own collection has provided their consent for you to e mail them, you should have clients choose-directly into your checklist a second time before you decide to deliver the 1st e mail. Which may appear to be a lot of hard work, however you are confirmed the individual definitely desires your email messages, which removes the possibility that you and your Internet service provider will come across problems.

Usually do not restrict your e-mails to a sales pitch. Your e-mails ought to have an e-newsletter structure, that contain details that the visitors will take pleasure in regarding your organization plus the market. Any e-mail which may seem like nothing but a marketing and advertising tactic will steer prospective customers to prefer-out quickly. Even when your news letter is ways to sell goods, your customers assume more than a sales hype.

To let the expansion of your marketing strategy, mix your advertising e-mails with social media marketing employing Facebook or myspace, Twitter, and other shops. This permits your prospects to not only build brand understanding, but additionally to share with you your site with other individuals with their social network. When this occurs, you could expect an increase in the actual size of your subscriber list.

Monitor this issue facial lines on e-e-mails that will get opened and people who usually do not. Generate a message with two different subject matter lines. Deliver an email together with the initial subject matter line to 1 / 2 of your listing, along with an email together with the secondly subject matter collection on the other 50 % of your listing. Become familiar with which topic collections possess the finest open costs and those folks ignore.

With which you found out about email marketing, you?re likely to want to ensure that your brain consumed every one of the readily available details. You ought to both look at this article once again or produce it out, to be able to apply it being a research in the future.

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Source: http://www.gotarticles.com/getting-far-better-at-email-marketing-with-one-of-these-great-ideas/

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Uruguay takes 'war on drugs' in new direction: The state as dealer

The South American country is proposing a state monopoly over marijuana in part to curtail drug-related violence. But it's getting pushback ? even from those in favor of legalization.

By Jonathan Gilbert,?Correspondent / September 19, 2012

Marijuana grower and activist Juan Vaz checks a Marijuana plants in Montevideo, August 9. Uruguay's government has sent a bill to Congress that would allow the state to grow and sell marijuana, a move that President Jose Mujica says will cut crime associated with illegal drug trafficking.

Andres Stapff/Reuters

Enlarge

Uruguay has long been at the vanguard of social reform in Latin America. Today, it is on the verge of passing into law one of its most radical ideas yet.

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The Broad Front ? the center-left coalition that holds power ? is proposing a state monopoly over the production and distribution of marijuana, making Uruguay the first national government to sell cannabis directly to citizens. The government says the measure is necessary to combat rising drug-related crime, decrease health risks for users, and counter ineffective US policies on drugs. But within Uruguay, interest groups have labeled the legislation totalitarian, while some international bodies argue it breaches global conventions.

?We?re putting this forward as international policy,? says Sebastian Sabini, president of the parliamentary commission created to debate the bill. ?The war on drugs has failed. There are more consumers and more violence.?

?Uruguay is opening up a new path,? he says.

Pushing the envelope

Uruguay is often overshadowed by the far larger economies of its neighbors Brazil and Argentina. But the country has made a name for itself with a long history of pushing the envelope on social issues.

In 1918, Uruguay became one of the first countries in the region to officially separate the state from the Roman Catholic Church. It implemented South America?s oldest mandatory pension system in 1896, and a bill to decriminalize abortion is expected to pass later this year.

But the bill proposing the legalization of marijuana has been denounced by the United Nations for breaching its 1961 convention on narcotics, and Uruguayans are also skeptical: Polls say just 40 percent approve.

?We?ll end up with people who don?t use marijuana buying it to sell on and make a quick buck,? says Hugo Lacasa, a street trader in Montevideo.

In early September, a parliamentary commission began a six-month debate to refine the bill, which will next be voted on in Congress. The Broad Front has a majority in both houses, but given the audacity of the proposal, President Jose Mujica, a former leftist guerrilla, has said it must have a minimum of 60 percent approval by lawmakers. Usually, just a 51 percent simple majority is required.

'Tackling' black market

The government introduced the bill in part because of ?the failure of the global ?war on drugs,? ? according to the text of the proposed law. It also believes that by separating the marijuana and hard drug markets, less people will become addicted to the latter ? especially "paco," a cocaine-based paste.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/Ql-RYtGsWz8/Uruguay-takes-war-on-drugs-in-new-direction-The-state-as-dealer

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Jobs bill for vets bogs down in Senate

WASHINGTON (AP) ? The Senate blocked legislation Wednesday that would have established a $1 billion jobs program putting veterans back to work tending to the country's federal lands and bolstering local police and fire departments.

Republicans said the spending authorized in the bill violated limits that Congress agreed to last year. Democrats fell two votes shy of the 60-vote majority needed to waive the objection, forcing the legislation back to committee.

Supporters loosely modeled their proposal after the President Franklin Delano Roosevelt's Civilian Conservation Corps used during the Great Depression to put people to work planting trees, building parks and constructing dams. They said the latest monthly jobs report, showing a nearly 11 percent unemployment rate for veterans of Iraq and Afghanistan, merited action from Congress.

Democratic lawmakers turned to the legislation shortly before they'll adjourn for the finals weeks of this year's election campaigns. The bill had little chance of passing the House this Congress, but it still allowed senators to appeal to a key voting bloc.

"(With) a need so great as unemployed veterans, this is not the time to draw a technical line on the budget," said Democratic Sen. Bill Nelson of Florida, the bill's lead sponsor, who faces a competitive re-election battle.

Republicans said the effort to help veterans was noble, but the bill was flawed nevertheless.

Sen. Tom Coburn of Oklahoma said the federal government already has six job-training programs for veterans and there is no way to know how well they are working. He argued that making progress on the country's debt was the best way to help veterans in the long-term.

"We ought to do nothing now that makes the problem worse for our kids and grandkids," Coburn said.

Democratic officials did not have an estimate for how many veterans would be hired as a result of the legislation. Sen. Patty Murray, D-Wash., said much would depend upon the number of applicants. She noted that more than 720,000 veterans are unemployed across the nation, including 220,000 veterans who have served since Sept. 11. She said putting veterans back to work was the cost of war.

"Instead of meeting us halfway, we have been met with resistance. Instead of saying yes to the nearly 1 million unemployed veterans, it seems some on the other side have spent the last week and a half seeking any way to say no," Murray said.

A handful of Republicans joined with Democrats in voting to waive the objection to the bill: Sen. Scott Brown of Massachusetts, Dean Heller of Nevada, Lisa Murkowski of Alaska and Maine's Susan Collins and Olympia Snowe. Brown and Heller are also in tough re-election contests.

Heller said he was proud to support the bill.

"After everything our veterans have done for us, the least we can do is make sure they are afforded every opportunity to thrive here at home," Heller said.

Source: http://news.yahoo.com/jobs-bill-vets-bogs-down-senate-164512360.html

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Seeing fewer older people in the street may lead low-income adults to fast-track their lives

[ Back to EurekAlert! ] Public release date: 18-Sep-2012
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Contact: Joan Robinson
joan.robinson@springer.com
49-622-148-78130
Springer

Study says people who live in deprived areas see fewer elderly and thus adapt to an environment in which life will be short

Why do people in deprived areas live life in the fast lane? It may be because of the age of people they observe in the street, according to a new study by Daniel Nettle and colleagues from Newcastle University in the UK. Their work suggests that because fewer older people are seen out in the street in deprived neighborhoods, younger generations assume that people die young. As a result, they may be adapting the speed at which they live their lives accordinglyfor example, by having children earlier in life. Nettle and team's work is published online in Springer's journal Human Nature.

The researchers looked at the 'social diet' or the daily distribution of types of people to whom one is exposed in two neighborhoods in Newcastle. One neighborhood was affluent, the other was poor. They walked through the main streets of both neighborhoods six times, recording the estimated ages of every man, woman, and child they passed. They then compared their recordings with census data, to establish how closely what people witness in the street reflects the actual age distribution of the population in these two neighborhoods.

They found that in the affluent neighborhood, more people over the age of 40 and over 60 in particular were seen than in the deprived area. In contrast, more young adults were observed on the streets in the poor neighborhood. However, this was not an accurate picture of the actual age distribution of residents in the two neighborhoods. In reality, more residents over 60 were living in the deprived area than in the affluent one. The authors comment that this discrepancy between what people see and the reality of who lives where is not a reflection of the different age profiles of people who live there, but rather of differences in the ways in which residents use the streets.

The authors conclude: "Chronic exposure to a world where there are many visible young adults and few visible old ones may activate psychological mechanisms that produce fast life-history strategies."

###

Reference

Nettle D et al (2012). No country for old men: street use and social diet in urban Newcastle. Human Nature. DOI 10.1007/s12110-012-9153-9

The full-text article is available to journalists on request.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


[ Back to EurekAlert! ] Public release date: 18-Sep-2012
[ | E-mail | Share Share ]

Contact: Joan Robinson
joan.robinson@springer.com
49-622-148-78130
Springer

Study says people who live in deprived areas see fewer elderly and thus adapt to an environment in which life will be short

Why do people in deprived areas live life in the fast lane? It may be because of the age of people they observe in the street, according to a new study by Daniel Nettle and colleagues from Newcastle University in the UK. Their work suggests that because fewer older people are seen out in the street in deprived neighborhoods, younger generations assume that people die young. As a result, they may be adapting the speed at which they live their lives accordinglyfor example, by having children earlier in life. Nettle and team's work is published online in Springer's journal Human Nature.

The researchers looked at the 'social diet' or the daily distribution of types of people to whom one is exposed in two neighborhoods in Newcastle. One neighborhood was affluent, the other was poor. They walked through the main streets of both neighborhoods six times, recording the estimated ages of every man, woman, and child they passed. They then compared their recordings with census data, to establish how closely what people witness in the street reflects the actual age distribution of the population in these two neighborhoods.

They found that in the affluent neighborhood, more people over the age of 40 and over 60 in particular were seen than in the deprived area. In contrast, more young adults were observed on the streets in the poor neighborhood. However, this was not an accurate picture of the actual age distribution of residents in the two neighborhoods. In reality, more residents over 60 were living in the deprived area than in the affluent one. The authors comment that this discrepancy between what people see and the reality of who lives where is not a reflection of the different age profiles of people who live there, but rather of differences in the ways in which residents use the streets.

The authors conclude: "Chronic exposure to a world where there are many visible young adults and few visible old ones may activate psychological mechanisms that produce fast life-history strategies."

###

Reference

Nettle D et al (2012). No country for old men: street use and social diet in urban Newcastle. Human Nature. DOI 10.1007/s12110-012-9153-9

The full-text article is available to journalists on request.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-09/s-sfo091812.php

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New LSU hospital leader once criticized Jindal for health-care cuts ...

BATON ROUGE -- The new leader of the LSU health-care system, working with Gov. Bobby Jindal's administration to make deep cuts to the public hospitals, earlier this year slammed the governor for slashing funding to the facilities.

"Yes, he is saving money. But to save money and lose your soul in doing so, I have to ask if that is the Christian way?" Frank Opelka wrote in a letter printed by The Advocate newspaper in February -- after midyear budget cuts hit university health programs.

Seven months later, Opelka is working side-by-side with the governor's health care secretary, Bruce Greenstein, to shrink far more spending on the safety net system of hospital and clinics that care for the uninsured.

In an interview with The Associated Press, Opelka said the newspaper letter was designed to draw attention to "our cut after cut strategy, which was not helping patients."

He said the Jindal administration isn't seeking such a strategy in the latest round of cuts, which Opelka is overseeing since his predecessor was ousted from the job after clashing with the administration over the budget reductions.

"I want us to be mindful of the impact. I don't think one cut after another is the best way to determine safety net care," said Opelka, LSU's executive vice president for health care and medical education redesign.

Opelka said the Jindal administration is pushing for collaborations with local community health providers to try to protect critical services and patient care.

"They don't want a cut strategy. They want a partnership strategy," Opelka said.

The Jindal administration has stripped a quarter of the health system's funding in response to a drop in federal Medicaid financing, and Jindal says LSU must change its model of providing services and embrace public/private partnerships.

The drop in funding is expected to reach more than $300 million in the next budget year that begins July 1.

In February, when Greenstein and Opelka's predecessor, Fred Cerise, were at odds over $34 million in cuts to the network of public hospitals and clinics, Opelka wrote that "this governor is slashing services to the most needy."

He said Jindal was "making changes that, were it not for the hope of Obamacare, are closing mental-health services, are limiting access to critical care and removing obstetrics care for the most needy."

The Republican Jindal opposes the federal health care revamp pushed by Democratic President Barack Obama and wants it repealed.

Cerise and the Jindal administration clashed when Cerise suggested provisions of the federal health overhaul law could help fill budget gaps in the LSU health care system.

Source: http://www.nola.com/politics/index.ssf/2012/09/new_lsu_hospital_leader_once_c.html

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A Ray of Hope

Every day until the election, Slate will offer up one reason to be optimistic for your candidate.

Really, Democrats? Do you really need to be more optimistic about Barack Obama?s chances than you were last night? Well, fine?here?s one thing you might have missed.

Today?s Good News for Obama: Check the new Pew poll, the first to ask voters what they really thought of Mitt Romney?s response to last week?s foreign attacks on U.S. diplomats. It confirms that Romney?s late-night decision to blame Obama?s weakness and ?sympathies? with flag-burners effectively took the heat off the president. By a 19-point margin, 45-26, ?adults? (not registered or likely voters) say they disapproved of Romney?s response. The GOP candidate effectively lost a week, on an issue he doesn?t win anyway.

Source: http://feeds.slate.com/click.phdo?i=c63a8b942f020b8f2685c817dcd2d462

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Illy Trieste Science Prize: Yuk Ming Dennis Lo awarded for non-invasive prenatal diagnosis

[ Back to EurekAlert! ] Public release date: 18-Sep-2012
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Contact: Cristina Serra
cserra@twas.org
39-040-224-0429
TWAS

The $100,000 prize, reserved for scientists from the developing world, was awarded at the TWAS 12th Conference in Tianjin, China, on 18 September 2012

Tianjin, China - The winner of the eighth edition of the Ernesto Illy Trieste Science Prize was announced today (Tuesday, 18 September 2012). The Prize rewards scientists living and working in developing countries whose research has had a significant impact on sustainable development. In previous years, the Ernesto Illy Trieste Science Prize has been awarded for research on climate change, renewable energy, and materials science. This year's Prize is awarded in the area of human health.

The winner received his award in front of an audience of more than 500 scientists, ministers of science and presidents of science academies from around the globe. The audience was convened by TWAS, the academy of sciences for the developing world, for the TWAS 12th General Conference and 23rd General Meeting held this week in Tianjin, China, and hosted by the Chinese Academy of Sciences.

Yuk Ming Dennis Lo, director of the Li Ka Shing Institute of Health Sciences and professor of medicine at the Chinese University of Hong Kong (CUHK), received the prestigious award for developing, with his team of researchers at CUHK, a ground-breaking technology for scanning the entire genome of a foetus from a blood sample obtained from its pregnant mother.

In 1997, Lo was able to demonstrate the presence of high concentrations of cell-free foetal DNA in the plasma of pregnant women, which could then be sampled and tested. This discovery opened up new possibilities for non-invasive prenatal diagnosis, and has effectively reduced our reliance on previous invasive and potentially risky, methods.

Lo commented: "The common procedures for prenatal diagnosis based on amniocentesis (the removal of amniotic fluid from the womb) and chorionic villus sampling (taking a piece of tissue from the placenta) are not entirely risk-free due to their invasiveness. To have a non-invasive test that can give certain answers and that can be followed over time in the womb, is a concrete help in obstetrics and brings tangible benefits to both the mother and the fetus, increasing the level of safety during pregnancy and reducing both the stress due to invasive tests. In the long-term, this technology will bring positive healthcare benefits to both developed and developing countries, reducing the suffering and health-care burden caused by genetic diseases."

The discovery trail

Lo graduated from Cambridge University and obtained his DPhil from the University of Oxford in 1994, but his heart remained in Hong Kong, the city where he was born, and he decided to return home in 1997. His move back to Asia was an opportunity to start a new research programme on a hitherto 'high risk' research area, namely, the investigation of extracellular DNA in plasma. Lo and colleagues had already noted the presence of tumour-derived DNA in the plasma and serum of cancer patients. This observation led Lo to wonder if he could also observe foetal DNA in the blood of pregnant women. At the same time, molecular biology techniques that are now widely used were just catching on. The 'real-time quantitative PCR' technique used by Lo allows scientists to amplify and quantify the DNA present in trace amounts in a sample (such as foetal DNA circulating in maternal plasma that, on average, accounts for 10 percent of the total DNA maternal plasma). Applying this technique to the analysis of the plasma of pregnant women, Lo was not only able to determine the sex of the foetus, but also the presence of diseases such as beta-thalassaemia that are inherited from the father.

In a further refinement of the analysis, Lo and his team showed that it was possible to follow the natural fluctuating levels of foetal DNA in maternal blood during pregnancy, and that traces of this DNA disappear within a few hours after birth. An important application of this study concerns some of the most common ailments associated with pregnancy, such as pre-eclampsia (characterized by oedema, proteinuria and hypertension) and pre-term delivery (which occurs between the 20th and the 37th completed week of gestation). In both cases, as Lo discovered, the detection of abnormal amounts of foetal DNA in maternal blood can then be used as a marker to monitor the progress of a pregnancy or to predict possible cases of at-risk pregnancies. In 2008, Lo applied the technique already used successfully for determining the sex of an unborn child and enhanced it to be able to identify foetuses with Down's syndrome. Down's syndrome (or trisomy 21) is characterized by the presence of three copies of chromosome 21 instead of the usual two, and causes a general slowing of psychomotor and intellectual development. Through the sequencing of millions of DNA molecules amplified from maternal plasma, Lo confirmed that it was possible to work out the proportions of each chromosome and hence detect Down's syndrome. The technique, now standardized, is used widely to detect Down's syndrome and other chromosomal aneuploidies (abnormalities in chromosome number structure) in China, Europe and the United States. The results of this research were published in the New England Journal of Medicine and now represent an important point of the prenatal diagnosis.

And Lo's development of prenatal diagnoses does not stop there. Two years ago, in 2010, it was the turn of the 'foetal genomic map', full of potential mutations, obtained by sequencing foetal DNA present in maternal plasma and comparing it with the maternal and paternal genomes.

With 28 patents filed based on his work, Lo is ensuring that his research efforts are being applied where it matters and have contributed to a paradigm shift in obstetrics care. With 300 articles published in international journals Lo has been made an honorary member of the Royal Society (2011) for his scientific achievements.

For all these reasons, Lo was selected as the 2012 recipient of the Ernesto Illy Trieste Science Prize in human health.

###


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Contact: Cristina Serra
cserra@twas.org
39-040-224-0429
TWAS

The $100,000 prize, reserved for scientists from the developing world, was awarded at the TWAS 12th Conference in Tianjin, China, on 18 September 2012

Tianjin, China - The winner of the eighth edition of the Ernesto Illy Trieste Science Prize was announced today (Tuesday, 18 September 2012). The Prize rewards scientists living and working in developing countries whose research has had a significant impact on sustainable development. In previous years, the Ernesto Illy Trieste Science Prize has been awarded for research on climate change, renewable energy, and materials science. This year's Prize is awarded in the area of human health.

The winner received his award in front of an audience of more than 500 scientists, ministers of science and presidents of science academies from around the globe. The audience was convened by TWAS, the academy of sciences for the developing world, for the TWAS 12th General Conference and 23rd General Meeting held this week in Tianjin, China, and hosted by the Chinese Academy of Sciences.

Yuk Ming Dennis Lo, director of the Li Ka Shing Institute of Health Sciences and professor of medicine at the Chinese University of Hong Kong (CUHK), received the prestigious award for developing, with his team of researchers at CUHK, a ground-breaking technology for scanning the entire genome of a foetus from a blood sample obtained from its pregnant mother.

In 1997, Lo was able to demonstrate the presence of high concentrations of cell-free foetal DNA in the plasma of pregnant women, which could then be sampled and tested. This discovery opened up new possibilities for non-invasive prenatal diagnosis, and has effectively reduced our reliance on previous invasive and potentially risky, methods.

Lo commented: "The common procedures for prenatal diagnosis based on amniocentesis (the removal of amniotic fluid from the womb) and chorionic villus sampling (taking a piece of tissue from the placenta) are not entirely risk-free due to their invasiveness. To have a non-invasive test that can give certain answers and that can be followed over time in the womb, is a concrete help in obstetrics and brings tangible benefits to both the mother and the fetus, increasing the level of safety during pregnancy and reducing both the stress due to invasive tests. In the long-term, this technology will bring positive healthcare benefits to both developed and developing countries, reducing the suffering and health-care burden caused by genetic diseases."

The discovery trail

Lo graduated from Cambridge University and obtained his DPhil from the University of Oxford in 1994, but his heart remained in Hong Kong, the city where he was born, and he decided to return home in 1997. His move back to Asia was an opportunity to start a new research programme on a hitherto 'high risk' research area, namely, the investigation of extracellular DNA in plasma. Lo and colleagues had already noted the presence of tumour-derived DNA in the plasma and serum of cancer patients. This observation led Lo to wonder if he could also observe foetal DNA in the blood of pregnant women. At the same time, molecular biology techniques that are now widely used were just catching on. The 'real-time quantitative PCR' technique used by Lo allows scientists to amplify and quantify the DNA present in trace amounts in a sample (such as foetal DNA circulating in maternal plasma that, on average, accounts for 10 percent of the total DNA maternal plasma). Applying this technique to the analysis of the plasma of pregnant women, Lo was not only able to determine the sex of the foetus, but also the presence of diseases such as beta-thalassaemia that are inherited from the father.

In a further refinement of the analysis, Lo and his team showed that it was possible to follow the natural fluctuating levels of foetal DNA in maternal blood during pregnancy, and that traces of this DNA disappear within a few hours after birth. An important application of this study concerns some of the most common ailments associated with pregnancy, such as pre-eclampsia (characterized by oedema, proteinuria and hypertension) and pre-term delivery (which occurs between the 20th and the 37th completed week of gestation). In both cases, as Lo discovered, the detection of abnormal amounts of foetal DNA in maternal blood can then be used as a marker to monitor the progress of a pregnancy or to predict possible cases of at-risk pregnancies. In 2008, Lo applied the technique already used successfully for determining the sex of an unborn child and enhanced it to be able to identify foetuses with Down's syndrome. Down's syndrome (or trisomy 21) is characterized by the presence of three copies of chromosome 21 instead of the usual two, and causes a general slowing of psychomotor and intellectual development. Through the sequencing of millions of DNA molecules amplified from maternal plasma, Lo confirmed that it was possible to work out the proportions of each chromosome and hence detect Down's syndrome. The technique, now standardized, is used widely to detect Down's syndrome and other chromosomal aneuploidies (abnormalities in chromosome number structure) in China, Europe and the United States. The results of this research were published in the New England Journal of Medicine and now represent an important point of the prenatal diagnosis.

And Lo's development of prenatal diagnoses does not stop there. Two years ago, in 2010, it was the turn of the 'foetal genomic map', full of potential mutations, obtained by sequencing foetal DNA present in maternal plasma and comparing it with the maternal and paternal genomes.

With 28 patents filed based on his work, Lo is ensuring that his research efforts are being applied where it matters and have contributed to a paradigm shift in obstetrics care. With 300 articles published in international journals Lo has been made an honorary member of the Royal Society (2011) for his scientific achievements.

For all these reasons, Lo was selected as the 2012 recipient of the Ernesto Illy Trieste Science Prize in human health.

###


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-09/t-its091812.php

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