Powell standing by Obama in 2012 presidential race

WASHINGTON (AP) ? Former Secretary of State Colin Powell, a longtime Republican, is sticking with President Barack Obama in this year's election.

He tells "CBS This Morning" he respects Mitt Romney but thinks he's been vague on many issues.

Speaking of Obama, Powell said the president got the United States out of Iraq and has laid out a plan for leaving Afghanistan "and didn't get us into any new wars."

He praises Obama's economic performance, saying that while difficult choices are ahead on taxes, spending and budgetary policies, "steadily, I think we've begun to come out of the dive and we're gaining attitude." Powell, a retired general, also formerly was a White House chief of staff and chairman of the military's Joint Chief of Staffs.

Powell says that he's still a Republican.

Source: http://news.yahoo.com/powell-standing-obama-2012-presidential-race-114641048--election.html

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Can't Ever Keep a Good Food Town Down ? Simmer & Boil ...

by Pableaux Johnson

No matter what happens, even the hell of high water, New Orleanians will gather as soon as possible around the table. These are our ways of surviving the communal tribulations: Sunday family dinners at Mandina?s; Monday night?s red beans simmering on the home stove; Holy Thursday green gumbo at Dooky Chase; and a good, solid po?boy sandwich or a dozen raw oysters just about anywhere in town. More than one person at the table in New Orleans is a congregation, with services held at late-night bars and neighborhood joints, always including the swapping of stories with friends?and often with strangers, too. The city is as blessed with natural good cooks and chefs as any other, but we do what we do without much of the ranking mentality you?ll find elsewhere. We?ll just send you to our special places to sample the food, drink, and common spirit that makes New Orleans the only possible home for us, the only place like it in America. Pull up a chair. You?re welcome any time.

Above, Dooky Chase friends and regulars gather with Creole legend and chef Leah Case (in red). Photography by Cedric Angeles.

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Source: http://simmerandboil.cookinglight.com/2012/10/24/neworleans/

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Up to 2,000 UK jobs at risk in Ford closures - union

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Source: http://news.yahoo.com/2-000-uk-jobs-risk-ford-closures-union-103345665--sector.html

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Lactation protein suppresses tumors and metastasis in breast cancer

ScienceDaily (Oct. 24, 2012) ? A protein that is necessary for lactation in mammals inhibits the critical cellular transition that is an early indicator of breast cancer and metastasis, according to research conducted at the University at Buffalo and Princeton University and highlighted as the cover paper in November issue of Nature Cell Biology.

"This is the first confirmed report that this protein, called Elf5, is a tumor suppressor in breast cancer," explains Satrajit Sinha, PhD, associate professor of biochemistry in the UB School of Medicine and Biomedical Sciences and a corresponding author on the paper with Yibin Kang, PhD, in the Department of Molecular Biology at Princeton University.

The researchers say the findings provide new avenues to pursue in treating and diagnosing breast cancer and possibly cancers of other organs as well. The paper includes findings from both animal and human breast cancer models.

Under normal circumstances, Elf5 is a transcription factor that controls the genes that allow for milk production.

But when the researchers used knockout mice developed at UB, in whom Elf5 was removed, they found more than just an inability to produce milk. They found that epithelial cells in the mammary glands also became more mesenchymal, that is, more like stem cells, an early harbinger of cancer, Sinha says.

"We found that when Elf5 levels are low or absent, epithelial cells become more like stem cells, morphing into mesenchymal cells, changing their shape and appearance and migrating elsewhere in the body," says Sinha. "This is how cancer spreads."

The UB-Princeton collaboration began when lead author Rumela Chakrabarti, PhD, originally a postdoctoral researcher in Sinha's laboratory at UB, took a position in the laboratory of Yibin Kang, PhD, Warner-Lambert/Parke-Davis Professor of Molecular Biology at Princeton, whose research focus is breast cancer metastasis. This allowed Chakrabarti to harness the expertise of the two laboratories to generate such a breakthrough finding.

"Elf5 keeps normal breast cells in their current shape and restricts their movement," says Chakrabarti. She found that the protein accomplishes this by suppressing the epithelial-mesenchymal transition by directly repressing transcription of Snail2, a master regulator of mammary stem cells known to trigger the EMT.

"Elf5 keeps Snail2 repressed, but once Elf5 is lost, then there is nothing to repress Snail 2," she explains.

The paper notes that Elf5 loss is frequently detected early in the disease at the breast hyperplasia stage, when the number of cells increases. In experiments conducted by the Princeton scientists, the researchers also found that little or no Elf5 in human breast cancer samples correlated with increased morbidity.

"It seems that loss of Elf5 is an initial event in the disease, so it could also be an important diagnostic tool," Sinha notes, which is a current focus of the UB and Princeton team.

"We want to know, how early does the loss of Elf5 occur? Could we use loss of Elf5 as a reliable diagnostic tool?" he asks.

The finding reveals the complex pathways through which breast cancers develop, he says, while also providing new avenues to pursue for diagnostics and treatments.

"Our research shows that the EMT-Snail 2 pathway is a valuable one to target for early breast cancer intervention," says Sinha, "possibly by designing something to recapture the repressive effect of Elf5 or a drug that could mimic Elf5 activity. And this is just one molecule, part of a big network. That's why we are now creating a detailed map of this molecule and its associated partners in order to give us a better idea of what to look for."

Other UB co-authors on the paper are Rose-Anne Romano, PhD, research assistant professor in biochemistry, and Kirsten Smalley, research technician. Other coauthors are: Julie Hwang, Mario Andres Blanco, Martin Lukacisin and Yong Wei from Princeton; Song Liu of Roswell Park Cancer Institute; Qifeng Yang and Bruce F. Haffty of the Department of Radiation Oncology in the University of Medicine and Dentistry of New Jersey and the Cancer Institute of New Jersey; and Toni Ibrahim, Laura Mercatali and Dino Amadori of the Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori in Italy.

The research was supported by the National Institutes of Health, the Department of Defense, Komen for the Cure, the Brewster Foundation and the Champalimaud Foundation.

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The above story is reprinted from materials provided by University at Buffalo, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Rumela Chakrabarti, Julie Hwang, Mario Andres Blanco, Yong Wei, Martin Luka?i?in, Rose-Anne Romano, Kirsten Smalley, Song Liu, Qifeng Yang, Toni Ibrahim, Laura Mercatali, Dino Amadori, Bruce G. Haffty, Satrajit Sinha, Yibin Kang. Elf5 inhibits the epithelial?mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nature Cell Biology, 2012; DOI: 10.1038/ncb2607

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/7X9jNEk8Njk/121024101531.htm

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Non-oil sectors likely to help Abu Dhabi beat growth estimate

Dubai: Abu Dhabi's economic growth this year will probably beat the government's estimates as non-oil industries in the richest emirate of the United Arab Emirates expand, the Department for Economic Development said.

"I expect it will be better than 3.9 per cent,-? undersecretary Mohamed Omar Abdulla said in an interview. "We encourage banks to go for productive activity to encourage the manufacturing and industry sectors.-? Growth will slow from 6.8 per cent in 2011 as global demand for oil weakens.

The Abu Dhabi government, which runs one of the world's richest sovereign wealth funds and is the biggest contributor to the United Arab Emirates' budget, is seeking to bolster non-oil industries. This year's forecast, which Abdulla said was 'conservative', exceeds the International Monetary Fund's 3.3 per cent estimate for global economic growth.

The emirate, which holds Standard & Poor's third-highest investment grade, expects non-oil output to accelerate at an average pace of 6.5 per cent a year through 2016. Non-oil industries, which accounted for 48 per cent of gross domestic product (GDP) in 2011, will expand 5.5 per cent in 2012 from 4.1 per cent last year, according to government forecasts.

Non-oil merchandise exports from the emirate's ports more than doubled in July compared with the same month last year and imports declined 6.7 per cent. The government published real GDP annual data for the first time this month.

Oil increase
"Beating estimates is always positive, but without historical data or any breakdown for 2012, it's hard to see which sectors may have performed better than expected,-? Khatija Haque, senior economist at Emirates NBD said.

"Oil production estimates for the UAE show a strong increase this year, so that may contribute to a better than expected outcome.
-?UAE oil production has risen 3 per cent so far this, according to data. Oil prices fell as low as $77.69 a barrel in June this year.

The price closed at $90.05 barrel on October 19. A number of the emirate's biggest companies are part-owned by the government. National Bank of Abu Dhabi, the nation's second-largest lender by assets, is 70 per cent owned by the Abu Dhabi Investment Council, and Aldar Properties, the emirate's largest developer, is 35 per cent owned by government-run Mubadala Development Company.

"The government has taken this responsibility, but with the aim to give it back,-? Abdulla said of state support of non-oil growth. "I don't know when is the correct time to give it back.-?

The IMF has long urged authorities in the Gulf Cooperation Council (GCC) to reduce their reliance on oil for growth to create more jobs and protect their economies from fluctuations in oil prices. Abu Dhabi holds about 6 percent of the world's proven reserves of crude.

Abu Dhabi is encouraging companies to sell shares as a means to help 'spread the wealth' and raise capital.

Source: http://www.timesofoman.com/innercat.aspx?detail=14706

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Domestic Short Hair - Orange and white - Frank - Large - Adult ...

Domestic Short Hair - Orange and white - Frank - Large - Adult

If you are looking for a big, happy go lucky guy, Frank's your cat. (and we mean big!) Currently weighing in at 20 pounds, Frank is the biggest cat here at Rude Ranch! Frank was originally adopted as a kitten. He lived with his humans for several years. However, when they retired and decided to travel full time, they felt that Frank would be happier in another home. Frank likes to watch birds and squirrels from the window and will chase the laser pointer with reckless abandon! Rude Ranch Animal Rescue does adoptions at various venues most weekends. Please come by and see our kitties available for adoption. Adoptions are also done directly out of the shelter by appointment only. Check our Events Calendar <http://www.ruderanch.petfinder.org> to see where we will be this weekend! ADOPTION FEE; The adoption fee is $50.00 which covers the kitty being altered, vaccinated (age appropriate), microchipped, tested for feline leukemia and feline aids, treated for fleas, ear mites and intestinal parasites

CHARACTERISTICS:
Breed: Domestic Short Hair - orange and white
Size: Large
Petfinder ID: 23052501

ADDITIONAL INFO:
Pet has been spayed/neutered

CONTACT:
Rude Ranch Animal Rescue | Annapolis, MD | 410-798-9559

For additional information, reply to this ad or see: http://www.petfinder.com/petnote/displaypet.cgi?petid=23052501

Brought to you by Petfinder.com

Source: http://baltimore.ebayclassifieds.com/cats-kittens/harwood/domestic-short-hair-orange-and-white-frank-large-adult/?ad=24148537

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Cancer Surgeon Leads Research

Oceanside (I-Newswire) October 23, 2012 - South Nassau Communities Hospital has named Shahriyour Andaz, MD, director of clinical research. Dr. Andaz, who also serves as South Nassau?s director of thoracic oncology, is a four-time winner of the Brooklyn and Long Island Chapter of the American College of Surgeons? prestigious Murray Friedman Resident Competition (clinical research) Award.

?It has been South Nassau?s goal to grow its research program, and I look forward to working with my colleagues to enhance the hospital?s scope of research initiatives and collaboration with researchers at other institutions,? said Dr. Andaz. ?Clinical trials serve as a testing ground for the latest medications, procedures or devices, and physicians are increasingly incorporating findings from clinical trials into their plan of patient care.?

A past recipient of the American College of Surgeons Commission on Cancer Outstanding Performance Award, Dr. Andaz is board-certified in both thoracic and general surgery and specializes in complex chest cancer procedures and robotic-assisted and minimally invasive thoracoscopic surgery.

He was the first surgeon on Long Island to perform robotic-assisted bilobectomy lung surgery and robotic-assisted surgical removal of the thymus gland. His expertise includes chest wall sarcoma resection and reconstruction, mesothelioma, tracheal resections and reconstructions, endobronchial surgery, esophageal resection and lung volume reduction surgery. Eliminating the need for large incisions and painful rib resections, the robotic-assisted and minimally invasive approaches offer faster healing and shortened recovery time.

Before joining South Nassau Communities Hospital in 2004, Dr. Andaz served at UCLA Medical Center?s Thoracic Surgery Department in 2003 and was an attending cardiothoracic surgeon from 2001-03 at Brookdale, Coney Island and Lutheran Hospitals and Maimonides Medical Center, where he was a Cardiothoracic Fellow from 1998-2001.

South Nassau?s Department of Clinical Research, based at its Gertrude & Louis Feil Cancer Center, is staffed by a clinical research nurse and a clinical research coordinator. A Protocol Review Committee, composed of a dozen members representing clinical specialties and support services, reviews all protocols and clinical studies to ensure alignment with the hospital?s mission. They are then forwarded to an Institutional Review Board that provides regulatory review, approval and monitoring of clinical trials conducted at the hospital to ensure the protection of human subjects.

This year some 70 patients are newly enrolled in clinical studies conducted by both hospital and community based physicians. Current research in nearly 20 studies at South Nassau is focusing on gastroenterology and lung, breast and colon cancer, neuro-oncology, bariatric and orthopedic studies, as well as protocols written by the nursing research/evidence-based practice council, chaired by Marybeth Ryan, Ph.D., R.N.

About South Nassau Communities Hospital:
South Nassau Communities Hospital is one of the region?s largest hospitals, with 435 beds, more than 900 physicians and 3,000 employees. Located in Oceanside, NY, the hospital is an acute-care, not-for-profit teaching hospital that provides state-of-the-art care in cardiac, oncologic, orthopedic, bariatric, pain management, mental health and emergency services. In addition to its extensive outpatient specialty centers, South Nassau provides emergency and elective angioplasty and is the only hospital on Long Island with the Novalis Tx? and Gamma Knife? Perfexion radiosurgery technologies. South Nassau is a designated Stroke Center by the New York State Department of Health and Comprehensive Community Cancer Center by the American College of Surgeons and is recognized as a Bariatric Surgery Center of Excellence by the American Society for Metabolic and Bariatric Surgery.

Company Contact Information
South Nassau Communities Hospital
Damian J. Becker
One Healthy Way
11572
Phone : 516-377-5370

Source: http://www.i-newswire.com/cancer-surgeon-leads-research/200006

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Kids choose Obama president again in 'Kids Pick the President' campaign

The president received 65 percent of the vote while former Gov. Mitt Romney earned 35 percent.

The announcement was made Monday by Linda Ellerbee, the Emmy Award-winning host of Nickelodeon's "Nick News."

To replicate the actual election as much as possible and ensure the results were more authentic, voting was limited to one vote per electronic device from Oct. 15 through Monday.

In the weeks leading up to the vote, the cable channel aired two election-themed "Nick News With Linda Ellerbee" specials which were the series? highest-rated specials so far in 2012.

In "Kids Pick the President: The Issues," which aired Sept. 17, kids across America ranked the campaign issues most important to them.

On Oct. 15, "Kids Pick the President: The Candidates" featured President Obama sitting down with "Nick News" at the White House to answer kids' questions. Romney was unavailable to tape his answers, according to his staff, so the special used previously taped video clips of him addressing issues raised by kids. Despite numerous requests over several months and an extension of the deadline to Monday, Romney was unable to participate in the special.

Since 1988, America's kids have picked five out of the last six presidents as elected by the populace. They missed the mark in 2004 when President George W. Bush defeated John Kerry.

Source: http://www.tulsaworld.com/site/articlepath.aspx?articleid=20121023_371_0_Moreth119747&rss_lnk=298,297

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U.S. to study cancer risks near 6 nuclear plants

The U.S. Nuclear Regulatory Commission announced plans Tuesday to launch a pilot epidemiological study of cancer risks near six nuclear power plants, including San Onofre Nuclear Generating Station in north San Diego County.

The commission is acting out of growing concern that using uranium to produce electricity may be dangerous even without accidents at nuclear plants. In addition, recent epidemiological studies in Germany and France suggest that the children living near nuclear reactors are twice as likely to develop leukemia.

The U.S. study will be conducted by the National Academy of Sciences, which will also help the commission determine whether to extend the study to all 65 U.S. nuclear power plants and certain nuclear fuel sites.

The pilot study will investigate cancer rates in each census tract within a 30-mile radius of the nuclear facilities, and assess cancers in children younger than 15 whose mothers lived near a nuclear facility during pregnancy. About 1 million people live within five miles of operating nuclear plants in the United States, and more than 45 million live within 30 miles, nuclear regulatory officials said.

The study will cost about $2 million and is to begin later this year, with the results available in 2014, commission spokesman Scott Burnell said. Before beginning, researchers will meet with communities near the plants to explain how the study will be conducted, Burnell said.

The academy chose sites that provide a broad representation of engineering designs and operating histories in states that have a variety of data retrieval systems in cancer registries.

The study area around the San Onofre Nuclear Generating Station, which has been out of commission since January because of equipment problems, encompasses 2.4 million people in more than 50 cities, including Laguna Beach, Huntington Beach, Costa Mesa, Santa Ana, Tustin, Lake Elsinore, Temecula, Oceanside, Escondido, Solana Beach and Camp Pendleton.

The last time officials assessed cancer rates near nuclear power plants was in 1990. The National Cancer Institute studied cancer risks posed by the 104 licensed reactors the commission governed at that time. The study concluded that the health risks, if any, were too small to be measured.

The commission has been relying on the results of that study ever since to inform the public about cancer mortality rates near nuclear reactors.

"I'm very pleased about this pilot study," said Roger Johnson, a retired neuroscience professor and member of the nonprofit environmental group San Clemente Green, which has raised safety and health concerns about San Onofre.

"Most people are focused on accidents at nuclear power plants," Johnson said. "They don't realize that they store tons of radioactive material and emit low levels of radioactive waste into the atmosphere."

louis.sahagun@latimes.com

Source: http://www.latimes.com/news/science/la-me-1024-san-onofre-cancer-20121024,0,7076665.story?track=rss

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