Mosquitoes bred to be incapable of transmitting malaria

ScienceDaily (June 12, 2012) ? Mosquitoes bred to be unable to infect people with the malaria parasite are an attractive approach to helping curb one of the world's most pressing public health issues, according to UC Irvine scientists.

Anthony James and colleagues from UCI and the Pasteur Institute in Paris have produced a model of the Anopheles stephensi mosquito -- a major source of malaria in India and the Middle East -- that impairs the development of the malaria parasite. These mosquitoes, in turn, cannot transmit the disease through their bites.

"Our group has made significant advances with the creation of transgenic mosquitoes," said James, a UCI Distinguished Professor of microbiology & molecular genetics and molecular biology & biochemistry. "But this is the first model of a malaria vector with a genetic modification that can potentially exist in wild populations and be transferred through generations without affecting their fitness."

More than 40 percent of the world's population lives in areas where there is a risk of contracting malaria. According to the Centers for Disease Control & Prevention, 300 million to 500 million cases of malaria occur each year, and nearly 1 million people die of the disease annually -- largely infants, young children and pregnant women, most of them in Africa.

James said one advantage of his group's method is that it can be applied to the dozens of different mosquito types that harbor and transmit the Plasmodium falciparum parasite, including those in Africa. Study results appear this week in the early online version of the Proceedings of the National Academy of Sciences.

The researchers conceived their approach through mouse studies. Mice infected with the human form of malaria create antibodies that kill the parasite. James' team exploited the molecular components of this mouse immune-system response and engineered genes that could produce the same response in mosquitoes. In their model, antibodies are released in genetically modified mosquitoes that render the parasite harmless to others.

"We see a complete deletion of the infectious version of the malaria parasite," said James, a member of the National Academy of Sciences. "This blocking process within the insect that carries malaria can help significantly reduce human sickness and death."

He and his colleagues have pioneered the creation of genetically altered mosquitoes that limit the transmission of dengue fever, malaria and other vector-borne illnesses.

Alison Isaacs, Nijole Jasinskiene and Mikhail Tretiakov of UCI and Isabelle Thiery, Agnes Zettor and Catherine Bourgouin of the Pasteur Institute contributed to the study, which received support from the National Institute of Allergy & Infectious Diseases -- a National Institutes of Health entity -- through grant number R37 AI029746.

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The above story is reprinted from materials provided by University of California - Irvine.

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Journal Reference:

  1. A. T. Isaacs, N. Jasinskiene, M. Tretiakov, I. Thiery, A. Zettor, C. Bourgouin, A. A. James. PNAS Plus: Transgenic Anopheles stephensi coexpressing single-chain antibodies resist Plasmodium falciparum development. Proceedings of the National Academy of Sciences, 2012; DOI: 10.1073/pnas.1207738109

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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Chavez makes energetic start in re-election bid

Venezuela's President Hugo Chavez waves to the crowd while riding atop a truck upon his arrival to the elections office in Caracas, Venezuela, Monday, June 11, 2012. Chavez rallied thousands of his supporters wearing his signature red beret and blowing kisses to the crowd as he formalized his presidential candidacy and launched his re-election bid.Second from left is Chavez's younger daugther Rosines and at right his brother Adan.(AP Photo/Ariana Cubillos)

Venezuela's President Hugo Chavez waves to the crowd while riding atop a truck upon his arrival to the elections office in Caracas, Venezuela, Monday, June 11, 2012. Chavez rallied thousands of his supporters wearing his signature red beret and blowing kisses to the crowd as he formalized his presidential candidacy and launched his re-election bid.Second from left is Chavez's younger daugther Rosines and at right his brother Adan.(AP Photo/Ariana Cubillos)

Opposition presidential candidate Henrique Capriles waves during a ceremony to register his candidacy for the presidency in Caracas, Venezuela, Sunday, June 10, 2012. Capriles will face Venezuela's President Hugo Chavez in the presidential elections scheduled for Oct. 7. (AP Photo/Ariana Cubillos)

Venezuela's President Hugo Chavez waves to the crowd while riding atop a truck upon his arrival to the elections office in Caracas, Venezuela, Monday, June 11, 2012. Chavez rallied thousands of his supporters wearing his signature red beret and blowing kisses to the crowd as he formalized his presidential candidacy and launched his re-election bid. (AP Photo/Ariana Cubillos)

Surrounded by supporters, opposition presidential candidate Henrique Capriles, center, gestures during a march before registering his candidacy for the presidency in Caracas, Venezuela, Sunday, June 10, 2012. Capriles will face Venezuela's President Hugo Chavez in the presidential elections scheduled for Oct. 7. (AP Photo/Fernando Llano)

Venezuela's President Hugo Chavez, left, delivers a speech as National Electoral Council President Tibisay Lucena, right, looks at him during a ceremony to register his candidacy for the presidency at the headquarters of the National Elections Council in Caracas, Venezuela, Monday, June 11, 2012. Chavez rallied thousands of his supporters Monday, wearing his signature red beret and singing a folk song as he formalized his presidential candidacy and launched his re-election bid. (AP Photo/Fernando Llano)

(AP) ? Venezuelan President Hugo is releasing a lengthy plan to deepen his socialist policies as he officially launches his campaign to win another six-year term in October.

Chavez's "Bolivarian Socialist" proposal was inserted in the government newspaper Ciudad CCS on Tuesday and is also distributed online.

It lays out broad goals such as to "continue building 21st century Bolivarian socialism" and to expand Venezuela's ties with allied countries.

The document also includes specific targets, such as increasing the country's food production by 45 percent. The oil-exporting country imports most of its food. Chavez presented the document to elections officials on Monday when he formally registered as a candidate.

Associated Press

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Medical Equipments and their essentialness in life

With advancements in technology, medical equipments are also getting upgraded. These can precisely be defined as instruments required by doctors in medical field. They can be used to diagnose a problem, monitor a patient?s condition, prevention, rehabilitation as well as help in their treatment.

Some of the major equipments used routinely include X-Ray machines, resonance imaging machines, therapeutic equipments like lasers, ECG monitors, blood pressure machines, surgery tables, oxygen cylinders, life support systems generally known as ventilators etc. Many of these equipments are used to identify critical situations being encountered by a patient.

Next section describes some of the prominent medical equipments that are being widely used.

? Medical Scale Equipments

These are used to measure accurate height & weight of a patient.

It is essential as dosage of some of the medicines is to be given according to prescribed weight and height. They are also capable of providing accurate as well as precise results.

? Veterinary Equipments

These are used to diagnose health problems related to pet animals such as cats, dogs, turtles, rabbits, kangaroos etc and mainly include surgical lightening, anesthesia, veterinary tables.

? Dermatologic Laser Equipments

They help in curing various skin problems like wrinkles, ageing, unwanted hair removal etc. Almost every dermatologist requires these equipments hence it is advised to get them financed.

? Hand Gloves

Hand gloves are integral part of every doctor?s life. They put on these gloves while performing their routine activities like surgeries, examining patients etc. Therefore they require best quality but cheap gloves which can be easily availed at many leading online stores.

? Optometry Equipments

These are used in eye care field. Some of the prominent equipments that are used in this category include rentinoscopes, vision charts, pen lights and so on. These are costly and financing of such equipments can save money.

? Medical Accounting Software

This software essentially deals with payment related details like payment and retrieval of balance, medical bills, payroll etc. this software saves large amount of efforts and time of hospital employees.

These equipments are very costly. You can even lease your medical equipments so that others can get benefit out of it when these are not being used. Fast approvals for equipments on lease can be availed. Many online stores are available which offer heavy discounts as well as extended warranty. Sometimes you may also get additional discounts plus some additional equipment absolutely free on every on-line order. Yet another option to get these equipments at lower rates is to get them financed and pay easy monthly installments.

?

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Earth From Space: Egypt From the International Space Station

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ScienceDaily: Biochemistry News

http://www.sciencedaily.com/news/matter_energy/biochemistry/ Read the latest research in biochemistry -- protein structure and function, RNA and DNA, enzymes and biosynthesis and more biochemistry news.en-usTue, 12 Jun 2012 23:05:01 EDTTue, 12 Jun 2012 23:05:01 EDT60
Media_httpwwwscienced_bcech
http://www.sciencedaily.com/news/matter_energy/biochemistry/ For more science articles, visit ScienceDaily.http://www.sciencedaily.com/releases/2012/06/120612145139.htm Researchers have created a computational tool to help predict how proteins fold by finding amino acid pairs that are distant in sequence but change together. Protein interactions offer clues to the treatment of disease, including cancer.Tue, 12 Jun 2012 14:51:51 EDThttp://www.sciencedaily.com/releases/2012/06/120612145139.htmhttp://www.sciencedaily.com/releases/2012/06/120612101458.htm A novel porous material that has unique carbon dioxide retention properties has just been developed.Tue, 12 Jun 2012 10:14:14 EDThttp://www.sciencedaily.com/releases/2012/06/120612101458.htmhttp://www.sciencedaily.com/releases/2012/06/120611193636.htm A newly developed carbon nanotube material could help lower the cost of fuel cells, catalytic converters and similar energy-related technologies by delivering a substitute for expensive platinum catalysts.Mon, 11 Jun 2012 19:36:36 EDThttp://www.sciencedaily.com/releases/2012/06/120611193636.htmhttp://www.sciencedaily.com/releases/2012/06/120611105311.htm New groundbreaking research has found that exposure to nanoparticles can have a serious impact on health, linking it to rheumatoid arthritis and the development of other serious autoimmune diseases. The findings have health and safety implications for the manufacture, use and ultimate disposal of nanotechnology products and materials. They also identified new cellular targets for the development of potential drug therapies in combating the development of autoimmune diseases.Mon, 11 Jun 2012 10:53:53 EDThttp://www.sciencedaily.com/releases/2012/06/120611105311.htmhttp://www.sciencedaily.com/releases/2012/06/120611092345.htm Researchers have created a reliable and fast flu-detection test that can be carried in a first-aid kit. The novel prototype device isolates influenza RNA using a combination of magnetics and microfluidics, then amplifies and detects probes bound to the RNA. The technology could lead to real-time tracking of influenza.Mon, 11 Jun 2012 09:23:23 EDThttp://www.sciencedaily.com/releases/2012/06/120611092345.htmhttp://www.sciencedaily.com/releases/2012/06/120610151304.htm Enabling bioengineers to design new molecular machines for nanotechnology applications is one of the possible outcomes of a new study. Scientists have developed a new approach to visualize how proteins assemble, which may also significantly aid our understanding of diseases such as Alzheimer's and Parkinson's, which are caused by errors in assembly.Sun, 10 Jun 2012 15:13:13 EDThttp://www.sciencedaily.com/releases/2012/06/120610151304.htmhttp://www.sciencedaily.com/releases/2012/06/120606155808.htm Using ultrafast, intensely bright pulses of X-rays scientists have obtained the first ever images at room temperature of photosystem II, a protein complex critical for photosynthesis and future artificial photosynthetic systems.Wed, 06 Jun 2012 15:58:58 EDThttp://www.sciencedaily.com/releases/2012/06/120606155808.htmhttp://www.sciencedaily.com/releases/2012/06/120606132316.htm A new voyage into "chemical space" ? occupied not by stars and planets but substances that could become useful in everyday life ? has concluded that scientists have synthesized barely one tenth of one percent of potential medicines. The report estimates that the actual number of these so-called "small molecules" could be one novemdecillion (that's one with 60 zeroes), more than some estimates of the number of stars in the universe.Wed, 06 Jun 2012 13:23:23 EDThttp://www.sciencedaily.com/releases/2012/06/120606132316.htmhttp://www.sciencedaily.com/releases/2012/06/120605121639.htm Halogens particularly chlorine, bromine, and iodine ? have a unique quality which allows them to positively influence the interaction between molecules. This ?halogen bonding? has been employed in the area of materials science for some time, but is only now finding applications in the life sciences.Tue, 05 Jun 2012 12:16:16 EDThttp://www.sciencedaily.com/releases/2012/06/120605121639.htmhttp://www.sciencedaily.com/releases/2012/06/120605102842.htm Researchers have developed a highly sensitive detector of infrared light that can be used in applications ranging from detection of chemical and biochemical weapons from a distance and better airport body scanners to chemical analysis in the laboratory and studying the structure of the universe through new telescopes.Tue, 05 Jun 2012 10:28:28 EDThttp://www.sciencedaily.com/releases/2012/06/120605102842.htmhttp://www.sciencedaily.com/releases/2012/06/120604092858.htm A new microscope enabled scientists to film a fruit fly embryo, in 3D, from when it was about two-and-a-half hours old until it walked away from the microscope as a larva.Mon, 04 Jun 2012 09:28:28 EDThttp://www.sciencedaily.com/releases/2012/06/120604092858.htmhttp://www.sciencedaily.com/releases/2012/06/120603191722.htm A new study suggests that the replication process for DNA -- the genetic instructions for living organisms that is composed of four bases (C, G, A and T) -- is more open to unnatural letters than had previously been thought. An expanded "DNA alphabet" could carry more information than natural DNA, potentially coding for a much wider range of molecules and enabling a variety of powerful applications, from precise molecular probes and nanomachines to useful new life forms.Sun, 03 Jun 2012 19:17:17 EDThttp://www.sciencedaily.com/releases/2012/06/120603191722.htmhttp://www.sciencedaily.com/releases/2012/05/120531165752.htm A laboratory test used to detect disease and perform biological research could be made more than 3 million times more sensitive, according to researchers who combined standard biological tools with a breakthrough in nanotechnology.Thu, 31 May 2012 16:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531165752.htmhttp://www.sciencedaily.com/releases/2012/05/120531145728.htm Scientists have demonstrated how the world's most powerful X-ray laser can assist in cracking the structures of biomolecules, and in the processes helped to pioneer critical new investigative avenues in biology.Thu, 31 May 2012 14:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531145728.htmhttp://www.sciencedaily.com/releases/2012/05/120531145720.htm Biochemists have designed specialized proteins that assemble themselves to form tiny molecular cages hundreds of times smaller than a single cell. The creation of these miniature structures may be the first step toward developing new methods of drug delivery or even designing artificial vaccines.Thu, 31 May 2012 14:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531145720.htmhttp://www.sciencedaily.com/releases/2012/05/120531145630.htm Ultrashort flashes of X-radiation allow atomic structures of macromolecules to be obtained even from tiny protein crystals.Thu, 31 May 2012 14:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120531145630.htmhttp://www.sciencedaily.com/releases/2012/05/120531102207.htm Our ability to "read" DNA has made tremendous progress in the past few decades, but the ability to understand and alter the genetic code, that is, to "rewrite" the DNA-encoded instructions, has lagged behind. A new study advances our understanding of the genetic code: It proposes a way of effectively introducing numerous carefully planned DNA segments into genomes of living cells and of testing the effects of these changes. New technology speeds up DNA "rewriting" and measures the effects of the changes in living cells.Thu, 31 May 2012 10:22:22 EDThttp://www.sciencedaily.com/releases/2012/05/120531102207.htmhttp://www.sciencedaily.com/releases/2012/05/120530152203.htm Researchers have developed a method for building complex nanostructures out of interlocking DNA "building blocks" that can be programmed to assemble themselves into precisely designed shapes. With further development, the technology could one day enable the creation of new nanoscale devices that deliver drugs directly to disease sites.Wed, 30 May 2012 15:22:22 EDThttp://www.sciencedaily.com/releases/2012/05/120530152203.htmhttp://www.sciencedaily.com/releases/2012/05/120530104034.htm Inexpensive, portable devices that can rapidly screen cells for leukemia or HIV may soon be possible thanks to a chip that can produce three-dimensional focusing of a stream of cells, according to researchers.Wed, 30 May 2012 10:40:40 EDThttp://www.sciencedaily.com/releases/2012/05/120530104034.htmhttp://www.sciencedaily.com/releases/2012/05/120530100041.htm Scientists have engineered cells that behave like AND and OR Boolean logic gates, producing an output based on one or more unique inputs. This feat could eventually help researchers create computers that use cells as tiny circuits.Wed, 30 May 2012 10:00:00 EDThttp://www.sciencedaily.com/releases/2012/05/120530100041.htmhttp://www.sciencedaily.com/releases/2012/05/120529113543.htm An integrated chemical chip has just been developed. An advantage of chemical circuits is that the charge carrier consists of chemical substances with various functions. This means that we now have new opportunities to control and regulate the signal paths of cells in the human body. The chemical chip can control the delivery of the neurotransmitter acetylcholine. This enables chemical control of muscles, which are activated when they come into contact with acetylcholine.Tue, 29 May 2012 11:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120529113543.htmhttp://www.sciencedaily.com/releases/2012/05/120528154859.htm Physicists have developed a method that models biological cell-to-cell adhesion that could also have industrial applications.Mon, 28 May 2012 15:48:48 EDThttp://www.sciencedaily.com/releases/2012/05/120528154859.htmhttp://www.sciencedaily.com/releases/2012/05/120528100253.htm Scientists have created and imaged the smallest possible five-ringed structure -- about 100,000 times thinner than a human hair. Dubbed 'olympicene', the single molecule was brought to life in a picture thanks to a combination of clever synthetic chemistry and state-of-the-art imaging techniques.Mon, 28 May 2012 10:02:02 EDThttp://www.sciencedaily.com/releases/2012/05/120528100253.htmhttp://www.sciencedaily.com/releases/2012/05/120527153818.htm Multi-walled carbon nanotubes riddled with defects and impurities on the outside could replace some of the expensive platinum catalysts used in fuel cells and metal-air batteries, according to scientists.Sun, 27 May 2012 15:38:38 EDThttp://www.sciencedaily.com/releases/2012/05/120527153818.htmhttp://www.sciencedaily.com/releases/2012/05/120527153718.htm Scientists have developed an ultra-sensitive test that should enable them to detect signs of a disease in its earliest stages.Sun, 27 May 2012 15:37:37 EDThttp://www.sciencedaily.com/releases/2012/05/120527153718.htmhttp://www.sciencedaily.com/releases/2012/05/120525103614.htm Images of the cell's transport pods have revealed a molecular version of the robots from Transformers. Previously, scientists had been able to create and determine the structure of 'cages' formed by parts of the protein coats that encase other types of vesicles, but this study was the first to obtain high-resolution images of complete vesicles, budded from a membrane.Fri, 25 May 2012 10:36:36 EDThttp://www.sciencedaily.com/releases/2012/05/120525103614.htmhttp://www.sciencedaily.com/releases/2012/05/120524143527.htm There's nothing like a new pair of eyeglasses to bring fine details into sharp relief. For scientists who study the large molecules of life from proteins to DNA, the equivalent of new lenses have come in the form of an advanced method for analyzing data from X-ray crystallography experiments.Thu, 24 May 2012 14:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120524143527.htmhttp://www.sciencedaily.com/releases/2012/05/120524123232.htm Researchers are using nanoparticles to simultaneously deliver proteins and DNA into plant cells. The technology could allow more sophisticated and targeted editing of plant genomes. And that could help researchers develop crops that adapt to changing climates and resist pests.Thu, 24 May 2012 12:32:32 EDThttp://www.sciencedaily.com/releases/2012/05/120524123232.htmhttp://www.sciencedaily.com/releases/2012/05/120524092932.htm Quantum physics and plant biology seem like two branches of science that could not be more different, but surprisingly they may in fact be intimately tied. Scientists have discovered an unusual quantum effect in the earliest stages of photosynthesis.Thu, 24 May 2012 09:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120524092932.htmhttp://www.sciencedaily.com/releases/2012/05/120523135527.htm Quantum computers may someday revolutionize the information world. But in order for quantum computers at distant locations to communicate with one another, they have to be linked together in a network. While several building blocks for a quantum computer have already been successfully tested in the laboratory, a network requires one additonal component: A reliable interface between computers and information channels. Austrian physicists now report the construction of an efficient and tunable interface for quantum networks.Wed, 23 May 2012 13:55:55 EDThttp://www.sciencedaily.com/releases/2012/05/120523135527.htmhttp://www.sciencedaily.com/releases/2012/05/120522152655.htm Rapid DNA sequencing may soon become a routine part of each individual's medical record, providing enormous information previously sequestered in the human genome's 3 billion nucleotide bases. Recent advances in sequencing technology using a tiny orifice known as a nanopore are covered in a new a article.Tue, 22 May 2012 15:26:26 EDThttp://www.sciencedaily.com/releases/2012/05/120522152655.htmhttp://www.sciencedaily.com/releases/2012/05/120521164104.htm Scientists have synthesized polymers to attach to proteins in order to stabilize them during shipping, storage and other activities. The study findings suggest that these polymers could be useful in stabilizing protein formulations.Mon, 21 May 2012 16:41:41 EDThttp://www.sciencedaily.com/releases/2012/05/120521164104.htmhttp://www.sciencedaily.com/releases/2012/05/120521163751.htm Scientists have devised a method for repeatedly encoding, storing and erasing digital data within the DNA of living cells. In practical terms, they have devised the genetic equivalent of a binary digit -- a "bit" in data parlance.Mon, 21 May 2012 16:37:37 EDThttp://www.sciencedaily.com/releases/2012/05/120521163751.htmhttp://www.sciencedaily.com/releases/2012/05/120521115654.htm Blood tests convey vital medical information, but the sight of a needle often causes anxiety and results take time. A new device however, can reveal much the same information as a traditional blood test in real-time, simply by shining a light through the skin. This portable optical instrument is able to provide high-resolution images of blood coursing through veins without the need for harsh fluorescent dyes.Mon, 21 May 2012 11:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120521115654.htmhttp://www.sciencedaily.com/releases/2012/05/120521103808.htm The plague, bacterial dysentery, and cholera have one thing in common: These dangerous diseases are caused by bacteria which infect their host using a sophisticated injection apparatus. Through needle-like structures, they release molecular agents into their host cell, thereby evading the immune response. Researchers have now elucidated the structure of such a needle at atomic resolution. Their findings might contribute to drug tailoring and the development of strategies which specifically prevent the infection process.Mon, 21 May 2012 10:38:38 EDThttp://www.sciencedaily.com/releases/2012/05/120521103808.htmhttp://www.sciencedaily.com/releases/2012/05/120518132657.htm Tiny beads may act as minimally invasive glucose sensors for a variety of applications in cell culture systems and tissue engineering.Fri, 18 May 2012 13:26:26 EDThttp://www.sciencedaily.com/releases/2012/05/120518132657.htmhttp://www.sciencedaily.com/releases/2012/05/120518081147.htm Using newly developed imaging technology, chemists have confirmed years of theoretical assumptions about water molecules, the most abundant and one of the most frequently studied substances on Earth.Fri, 18 May 2012 08:11:11 EDThttp://www.sciencedaily.com/releases/2012/05/120518081147.htmhttp://www.sciencedaily.com/releases/2012/05/120517193141.htm Researchers have come closer to solving an old challenge of producing graphene quantum dots of controlled shape and size at large densities, which could revolutionize electronics and optoelectronics.Thu, 17 May 2012 19:31:31 EDThttp://www.sciencedaily.com/releases/2012/05/120517193141.htmhttp://www.sciencedaily.com/releases/2012/05/120517143506.htm Scientists have discovered how adding trace amounts of water can tremendously speed up chemical reactions -? such as hydrogenation and hydrogenolysis ?- in which hydrogen is one of the reactants, or starting materials.Thu, 17 May 2012 14:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120517143506.htmhttp://www.sciencedaily.com/releases/2012/05/120514104848.htm Three proteins have been found to be involved in the accumulation of fatty acids in plants. The discovery could help plant scientists boost seed oil production in crops. And that could boost the production of biorenewable fuels and chemicals.Mon, 14 May 2012 10:48:48 EDThttp://www.sciencedaily.com/releases/2012/05/120514104848.htmhttp://www.sciencedaily.com/releases/2012/05/120510095622.htm A new approach to generating terahertz radiation will lead to new imaging and sensing applications. The low energy of the radiation means that it can pass through materials that are otherwise opaque, opening up uses in imaging and sensing ? for example, in new security scanners. In practice, however, applications have been difficult to implement.Thu, 10 May 2012 09:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120510095622.htmhttp://www.sciencedaily.com/releases/2012/05/120509135959.htm To better understand how microRNAs -- small pieces of genetic material -- influence human health and disease, scientists first need to know which microRNAs act upon which genes. To do this scientists developed miR-TRAP, a new easy-to-use method to directly identify microRNA targets in cells.Wed, 09 May 2012 13:59:59 EDThttp://www.sciencedaily.com/releases/2012/05/120509135959.htmhttp://www.sciencedaily.com/releases/2012/05/120508173349.htm Researchers have boosted the efficiency of a novel source of white light called quantum dots more than tenfold, making them of potential interest for commercial applications.Tue, 08 May 2012 17:33:33 EDThttp://www.sciencedaily.com/releases/2012/05/120508173349.htmhttp://www.sciencedaily.com/releases/2012/05/120508152129.htm Chemists have designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly 3,000 times.Tue, 08 May 2012 15:21:21 EDThttp://www.sciencedaily.com/releases/2012/05/120508152129.htmhttp://www.sciencedaily.com/releases/2012/05/120503194229.htm Researchers have developed a prototype bioreactor that both stimulates and evaluates tissue as it grows, mimicking natural processes while eliminating the need to stop periodically to cut up samples for analysis.Thu, 03 May 2012 19:42:42 EDThttp://www.sciencedaily.com/releases/2012/05/120503194229.htmhttp://www.sciencedaily.com/releases/2012/05/120503120130.htm A new technique predictably generates complex, wavy shapes and may help improve drug delivery and explain natural patterns from brain folds to bell peppers.Thu, 03 May 2012 12:01:01 EDThttp://www.sciencedaily.com/releases/2012/05/120503120130.htmhttp://www.sciencedaily.com/releases/2012/05/120502132953.htm Liquid crystals, the state of matter that makes possible the flat screen technology now commonly used in televisions and computers, may have some new technological tricks in store.Wed, 02 May 2012 13:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120502132953.htmhttp://www.sciencedaily.com/releases/2012/05/120502112910.htm A new nanotube super sensor is able to detect subtle differences with a single sniff. For example, the chemical dimethylsulfone is associated with skin cancer. The human nose cannot detect this volatile but it could be detected with the new sensor at concentrations as low as 25 parts per billion.Wed, 02 May 2012 11:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120502112910.htmhttp://www.sciencedaily.com/releases/2012/05/120502091839.htm A new biomimetic approach to synthesising polymers will offer unprecedented control over the final polymer structure and yield advances in nanomedicine, researchers say.Wed, 02 May 2012 09:18:18 EDThttp://www.sciencedaily.com/releases/2012/05/120502091839.htmhttp://www.sciencedaily.com/releases/2012/05/120501085502.htm Scientists using high-powered microscopes have made a stunning observation of the architecture within a cell ? and identified for the first time how the architecture changes during the formation of gametes, also known as sex cells, in order to successfully complete? the process.Tue, 01 May 2012 08:55:55 EDThttp://www.sciencedaily.com/releases/2012/05/120501085502.htmhttp://www.sciencedaily.com/releases/2012/04/120430151752.htm Biomedical engineers have demonstrated the first all-polymeric bone scaffold that is fully biodegradable and offers significant mechanical support during repair. The technique uses silk fibers to reinforce a silk matrix. Adding microfibers to the scaffolds enhances bone formation and mechanical properties. It could improve repair after accident or disease.Mon, 30 Apr 2012 15:17:17 EDThttp://www.sciencedaily.com/releases/2012/04/120430151752.htmhttp://www.sciencedaily.com/releases/2012/04/120430114937.htm Cells regulate their functions by adding or subtracting phosphates from proteins. If scientists could study the process in detail, in individual cells over time, understanding and treating diseases would be greatly aided. Formerly this was impossible without damaging the cells or interfering with the process itself, but scientists have now achieved the goal by using bright infrared beams and a technique called Fourier transform spectromicroscopy.Mon, 30 Apr 2012 11:49:49 EDThttp://www.sciencedaily.com/releases/2012/04/120430114937.htmhttp://www.sciencedaily.com/releases/2012/04/120430105356.htm Researchers have shown how small random patches of disordered, frozen electric charges can make a difference when they are scattered on surfaces that are overall neutral. These charges induce a twisting force that is strong enough to be felt as far as nanometers or even micrometers away. These results could help scientists to understand phenomena that occur on surfaces such as those of large biological molecules.Mon, 30 Apr 2012 10:53:53 EDThttp://www.sciencedaily.com/releases/2012/04/120430105356.htmhttp://www.sciencedaily.com/releases/2012/04/120427100113.htm Engineers have found a novel method for "decorating" nanowires with chains of tiny particles to increase their electrical and catalytic performance. The new technique is simpler, faster and more effective than earlier methods and could lead to better batteries, solar cells and catalysts.Fri, 27 Apr 2012 10:01:01 EDThttp://www.sciencedaily.com/releases/2012/04/120427100113.htmhttp://www.sciencedaily.com/releases/2012/04/120425140403.htm Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. Chemists have taken this kind of design a step further; Using computational methods, they have created the first custom-designed protein crystal.Wed, 25 Apr 2012 14:04:04 EDThttp://www.sciencedaily.com/releases/2012/04/120425140403.htmhttp://www.sciencedaily.com/releases/2012/04/120423104019.htm Researchers have advanced the ability to view a clear picture of a single cellular structure in motion. By identifying molecules using compressed sensing, this new method provides needed spatial resolution plus a faster temporal resolution.Mon, 23 Apr 2012 10:40:40 EDThttp://www.sciencedaily.com/releases/2012/04/120423104019.htmhttp://www.sciencedaily.com/releases/2012/04/120422162415.htm What does lemon pan sauce chicken have to do with biochemistry and molecular biology? Some will say that successful execution of the dish requires the Maillard reaction, a chemical process that's responsible for the flavors and colors in a variety of food.Sun, 22 Apr 2012 16:24:24 EDThttp://www.sciencedaily.com/releases/2012/04/120422162415.htmhttp://www.sciencedaily.com/releases/2012/04/120422134953.htm Researchers have revealed how protons move in phosphoric acid in a study that sheds new light on the workings of a promising fuel cell electrolyte.Sun, 22 Apr 2012 13:49:49 EDThttp://www.sciencedaily.com/releases/2012/04/120422134953.htmhttp://www.sciencedaily.com/releases/2012/04/120419132602.htm Researchers have developed a technique for encapsulating liquids of nanocrystals between layers of graphene so that chemical reactions in the liquids can be imaged with an electron microscope. With this technique, movies can be made that provide unprecedented direct observations of physical, chemical and biological phenomena that take place in liquids on the nanometer scale.Thu, 19 Apr 2012 13:26:26 EDThttp://www.sciencedaily.com/releases/2012/04/120419132602.htmhttp://www.sciencedaily.com/releases/2012/04/120419121523.htm Researchers may have found a way to protect us against otherwise deadly chemical attacks, such as the subway sarin incident in Tokyo that left thirteen people dead and thousands more injured or with temporary vision problems. The method is based on a new and improved version of a detoxifying enzyme produced naturally by our livers, according to a new reportThu, 19 Apr 2012 12:15:15 EDThttp://www.sciencedaily.com/releases/2012/04/120419121523.htm

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HBT: Rivera finally undergoes knee surgery

All Star Game Logo

Biggest move: at catcher, where Buster Posey has passed Yadier Molina. ?The results: Catcher Buster Posey: 1,713,839 Yadier Molina: 1,576,199 First Base Joey Votto: 2,108,725 Lance Berkman:851,373 Second Base Dan Uggla: 1,341,088 Brandon Phillips:885,250 Third Base David Wright: 1,358,992 Pablo Sandoval:1,103,650 Shortstop Troy Tulowitzki:1,200,256 Rafael Furcal: 1,183,096 Outfield Matt Kemp: 2,589,464 Carlos Beltran: 1,782,831 Ryan?

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C Spire announces it's getting the Galaxy S III

Samsung Galaxy S III

The march of the Galaxy S III continues, with regional carrier C Spire announcing that it plans to carry Samsung's latest. Pricing and availability will be relayed "in the coming weeks," said the carrier formerly known as Cellular South. The GSIII will be one of C Spire's first LTE-capable devices, and the 4G network is still slated to launch in 20 markets in Mississippi in September.

C Spire didn't specify whether it'll carry both the 16- and 32-gigabyte versions of the phone, but it did mention that "it comes" in marble white and pebble blue, which suggests it'll carry both colors.

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Coordinated bombs kill 56 during Iraq pilgrimage

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Statins May Leave Patients With Less Energy: Study

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